By car
Seeing Utrecht by car is not recommended. The city planners have made it as difficult as possible to navigate the city center, to try and discourage cars there. Driving around can be frustrating as the center is fraught with bus-only lanes, one-way streets, traffic lights and terribly expensive parking spaces. If you want to come by car it is recommended to park at one of the P+R Park and Ride (http://www.utrechtpenr.nl/) places, and take a cheap shuttle bus or tram service into town. There are also several parking garages closer to the center, but they are more expensive.
By Tram
In Utrecht there is a tram line from central station to southern suburbs Nieuwegein and IJsselstein. For tourists, only the the first stops will be interesting, Westplein and Graadt van Roggeweg. These are located next to the Turkish neighbourhood and the main convention centre respectively.